Fondation MEDIC

www.fondation-medic.ch

The MEDIC day

[14.10.2016]

Why?

In order to foster contact between the research groups supported by the MEDIC foundation each year a meeting is organised, during which the consortium members present their latest research results and also ideas for new projects. The intention of this meeting is to intensify exchange and where possible to stimulate new activities in which different groups in the consortium collaborate. The meeting is as a rule attended by (members of) the Scientific Advisory Board, who engage in discussions with the presenting scientists and use this setting to judge the progress made. The MEDIC day is not only attended by the principal investigators but also by (a selection of) the junior scientists working in the group (postdocs and graduate students).

When and where?

The MEDIC day is organised as a rule in Lausanne, and covers an afternoon of scientific reports and discussions, an evening informal dinner and another full day of scientific exchange the day after. The program of the day illustrates the array of activities deployed by the partners in the consortium.

 

The programme of the MEDIC day 2016 (provisional)

November 21-21, 2016 – Hotel de la Paix, Lausanne

Monday, November 21
13.00-13.30 Coffee
13.30-13.35 Opening
13.35-14.15 Marie-Agnès Doucey Tie2 expressing monocytes in breast cancer promote protective anti-tumor immune responses
14.15-14.55 Curzio Ruegg Unraveling mechanisms of breast cancer dormancy
14.55-15.40 Didier Picard Regulators of estrogen receptor alpha activity and their role in breast cancer
15.40-16.00 Break
16.00-16.40 Christos Sotiriou Interrogating breast cancer heterogeneity
16.40-17.20 Karen Willard Exploring the immune infiltrate in human breast cancer
17.20-18.00 Laurence de Leval Characterization of molecular biomarkers relevant to the biology of peripheral T-cell lymphomas
18.30 Apéritif and dinner (Restaurant Hotel de la Paix)
Tuesday, November 22
08.30-09.10 Nicolo Riggi Epigenetic mechanisms in the development of desmoplastic small cround cell tumours
09.10-09.50 Tom McKee Comprehensive molecular characterization of colorectal cancer metastases
09.50-10.15 Break
10.15-10.55 Mauro Delorenzi Linking molecular heterogeneity of colon cancer with clinically useful subtypes
10.55-11.35 Tanya Petrova Mechanisms of resistance to anti-angiogenic therapy in colorectal cancer
11.35-12.15 Ghanem Ghanem /
Fabrice Journé
Melanogenesis in melanoma progression and therapy
12.15-13.30 Lunch
13.30-14.10 Nathalie Rufer Identifying high-avidity and high-quality individual T-cells in melanoma patients
14.10-14.55 Pedro Romero Harnessing T-cells for cancer immunotherapy
14.55-15.15 Break
15.15-15.55 Camille Jandus Killer CD4 T-cells: a novel candidate for human tumor Immunotherapy
15.55-16.35 Paul Walker The impact of T cell and glioblastoma adaptations to hypoxia on anti-tumour immunity
16.35 Concluding remarks
The programme of the MEDIC day 2015

November 05-06, 2015 – Hotel de la Paix, Lausanne

Thursday, November 05
13.00-13.30 Coffee
13.30-13.35 Opening
13.35-14.15 Marie-Agnès Doucey Reprogramming Tie2 expressing monocytes in breast cancer to promote protective anti-tumor immune responses
14.15-14.55 Curzio Ruegg /
Girieca Lorusso
Unraveling mechanisms of breast cancer metastasis and dormancy
14.55-15.35 Gregory Segala Regulation of the activity of the estrogen receptor α by Vps-C complex components and their role in breast cancer
Marco Pupo GPER signaling in cancer-associated fibroblasts
15.35-16.00 Break
16.00-16.40 Christine Desmedt Dissecting the impact of breast cancer heterogeneity on disease dissemination and progression
16.40-17.20 Tom McKee Is the molecular make-up of primary and metastatic colorectal cancer identical?
17.20-18.00 Ivan Stamenkovic Mechanisms involved in the pathogenesis of synovial sarcoma
18.30 Apéritif and dinner (Restaurant Hotel de la Paix)
Friday, November 06
08.30-09.10 Laurence de Leval Mutational landscape of angioimmunoblastic T-cell lymphoma
09.10-09.50 Philippe Lewalle Role of immune micro-environment in acute leukemia: epigenetics
09.50-10.30 Mauro Delorenzi Linking molecular heterogeneity of colon cancer with clinically useful subtypes
10.30-11.00 Break
11.00-11.40 Tanya Petrova Mechanisms of resistance to anti-angiogenic therapy in colorectal cancer
11.40-12.20 Ghanem Ghanem /
Fabrice Journé
Melanogenesis in melanoma progression and therapy
12.20-14.00 Lunch
14.00-14.40 Karen Willard The importance of tumor infiltrating lymphocyte density, subset composition and organization in breast cancer
14.40-15.20 Amélie Cachot Killer CD4 T cells: a novel candidate for human tumor immunotherapy
15.20-15.45 Break
15.45-16.25 Nathalie Rufer Identifying high-avidity and high-quality T-cells in individual melanoma patients
16.25-17.05 Paul Walker /
Marta Calvo Tardon
The impact of T cell and glioblastoma adaptations to hypoxia on anti-tumour immunity
17.05-17.45 Nicolo Riggi Epigenetic mechanisms in the development of pediatric tumors
17.45 General discussion
and closure
The programme of the MEDIC day 2014

November 13-14, 2014 – Hotel de la Paix, Lausanne

Thursday, November 13
13.00-13.30 Coffee
13.30-13.45 Opening
13.35-14.20 Marie-Agnès Doucey Reprogramming Tie2 expressing monocytes in breast cancer to promote protective anti-tumor immune responses
14.20-15.05 Curzio Ruegg Unraveling mechanisms of breast cancer dormancy
15.05-15.50 Grégory Ségala /
Marcela Bennesch
Regulators of estrogen receptor alpha activity and their role in breast cancer (group Didier Picard)
15.50-16.15 Break
16.15-17.00 Christos Sotiriou Dissecting the impact of breast cancer heterogeneity on disease dissemination and progression
17.00-17.30 Karen Willard The importance of tumor infiltrating lymphocyte density, subset composition and organization in breast cancer
17.30-18.00 Lukas Flatz MEDIC prize 2014 lecture:
Improved melanoma immunotherapy by deciphering the differences of simultaneously induced T cell responses against auto-, neo- and viral antigens
18.30 Apéritif and dinner (Restaurant Hotel de la Paix)
Friday, November 14
08.30-09.15 Laurence de Leval /
David Vallois
Mutational landscape of angioimmunoblastic T-cell lymphoma
09.15-10.00 Mauro Delorenzi Linking molecular heterogeneity of colon cancer with clinically useful subtypes
10.00-10.30 Break
10.30-11.15 Anita Wolfer Role of MYC in treatment resistance
11.15-12.00 Tanya Petrova Mechanisms of resistance to anti-angiogenic therapy in colorectal cancer
12.00-13.30 Lunch
13.30-14.15 Pedro Romero Harnessing T-cells for cancer immunotherapy
14.15-14.45 Paul Walker The impact of T cell and glioblastoma adaptations to hypoxia on anti-tumour immunity
14.45-15.15 Break
15.15-16.00 Group Philippe Martiat Role of immune micro-environment in acute leukemia: epigenetics
16.00-16.45 Ghanem Ghanem /
Fabrice Journé
Melanogenesis in melanoma progression and therapy
16.45 General discussion
The programme of the MEDIC day 2013

November 11-12, 2013 – Hotel de la Paix, Lausanne

Monday, November 11
13.00-13.30 Coffee
13.30-13.45 Opening
13.45-14.30 Marie-Agnès Doucey Pro-angiogenic monocytes in breast cancer
14.30-15.00 Agnese Mariotti Function of the transcription factor Sox10 in the mammary gland and in breast cancer
15.00-15.45 Didier Picard Regulators of estrogen receptor alpha activity and their role in breast cancer
15.45-16.15 Break
16.15-17.00 Matteo Torsello /
Anita Wolfer
The role of MYC in cancer cell motility
17.00-17.30 Laurence Buisseret MEDIC prize 2012 lecture: Organized Immune Responses in Breast Cancer
18.30 Aperitif and dinner
Tuesday, November 12
08.30-09.15 Ivan Stamenkovic Energy regulation of cancer stem cells
09.15-10.00 Curzio Ruegg Unraveling the role of MAGI1 and CYR6 in cancer progression and therapy
10.00-10.45 Christine Desmedt /
Michail Ignatiadis
Molecular heterogeneity drives metastasis in breast cancer
10.45-11.15 Break
11.15-12.00 Philippe Martiat Role of immune micro-environment in acute leukemia
12.00-12.45 Pedro Romero Role of miRNA-155 in CD8+ T-cell function
12.45-14.00 Lunch
14.00-14.45 Laurence de Leval /
P Dobey
Molecular characterization of nodal peripheral T-cell lymphomas
14.45-15.30 Ghanem Ghanem /
Fabrice Journé
Melanogenesis in melanoma progression and therapy
15.30-16.00 Break
16.30-17.15 Mauro Delorenzi /
Edoardo Missiaglia
Molecular genetic heterogeneity of colon cancer
17.15-18.00 Tania Petrova Role and targeting of Prox1 in colon cancer metastasis
The programme of the MEDIC day 2012
Wednesday, October 24
Anita Wolfer MEDIC prize 2011 lecture: The role of Myc in cellular invasion and metastasis
Ivan Stamenkovic Energy regulation of glioblastoma stem cells
Mauro Delorenzi Linking molecular genetic heterogeneity of colon cancer with clinically useful subtypes
Tania Petrova Role and targeting of Prox1 in colon cancer metastasis
Curzio Ruegg Unraveling the role of MAGI1 and CYR6 in tumor progression and therapy
Thursday, October 25
Christos Sotiriou Molecular heterogeneity drives metastasis in breast cancer
Agnese Mariotti Sox10 function in mammary gland and breast cancer
Didier Picard Pharmacological and genetic investigations of estrogen-regulated and other cancers
Marie-Agnès Doucey Pro-angiogenic monocytes in breast cancer
Ghanem Ghanem Melanogenesis in melanoma progression and therapy
Edoardo Missiaglia (LdL) Molecular biomarkers in peripheral T-cell lymphoma
Philippe Martiat Role of immune micro-environment in acute leukemia
Jan Dudda (P.Romero) MicroRNA-155 is promoting tumor-specific CD8+ T cells
The programme of the MEDIC day 2011
A. Mariotti Function of MFG-E8/lactadherin in cancer progression
C. Ruegg Heterotypic interactions in the tumor microenvironment: contribution to tumor metastasis
V. Piguet Global analysis of transcription reveals BCSC-1 as a melanoma tumor suppressor that downregulates MITF
G. Ghanem New treatments, new markers in melanoma
L. Julien Proangiogenic programming of CD11b+ myelomonocytes in breast cancer by PlGF during hematopoietic progenitors differentiation
M. Delorenzi Analysis of Molecular Profiles and Gene Expression in clinical samples of colon cancer
C. Sotiriou Update on the results of the breast cancer stroma project and introduction to our new research program on breast cancer molecular heterogeneity
D. Picard Mechanistic studies on signalling crosstalk by the estrogen receptor alpha suggest new therapeutic schemes for breast cancer
T. Petrova Transcriptional control of colon cancer
P. Martiat The immuno-blood and marrow environment in acute leukemia: a study of natural and induced Tregs and a transcriptomic analysis of infiltrating CD3
P. Romero Role of microRNA in CD8 T cell functions